Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | CCR5 | P51681 | 2/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6983768 | 0.87 | ACHE (0.35) | ACHEMAOBTPSAB1KCNH2BCHE | |
| Hydrochloric Acid SCHEMBL6976629 | 0.86 | ACHE (0.35) | ACHEMAOBTPSAB1BCHE | |
| SCHEMBL6982741 | 0.82 | ACHE (0.35) | ACHEMAOB | |
| Hydrochloric Acid SCHEMBL6984600 | 0.80 | TPSAB1 (0.33) | ACHEMAOBTPSAB1DPP4EPHX2 | |
| SCHEMBL6985682 | 0.77 | SLC6A4 (0.49) | — | |
| SCHEMBL6985715 | 0.75 | KCNA3 (0.42) | — | |
| SCHEMBL6985201 | 0.75 | EPHX2 (0.45) | TPSAB1EPHX2 | |
| Hydrochloric Acid SCHEMBL6978492 | 0.75 | EPHX2 (0.45) | EPHX2 | |
| SCHEMBL6986388 | 0.75 | SLC6A4 (0.45) | ACHEMAOBBCHE | |
| Hydrochloric Acid SCHEMBL6982769 | 0.74 | SLC6A4 (0.44) | ACHEMAOBBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0923575-B1 | CYCLIC ETHER COMPOUNDS AS SODIUM CHANNEL MODULATORS | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-03-12 | — | — | EP | disclosed |
| US-6172085-B1 | CENTRAL NERVOUS SYSTEM AND PSYCHOLOGICAL DISORDERS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-01-09 | — | — | US | disclosed |