Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | DRD3 | P35462 | 2/20 | 0.36 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6978492 | 0.99 | EPHX2 (0.45) | EPHX2ALDH1A1DRD2DRD3FKBP1A | |
| SCHEMBL6975786 | 0.92 | POLB (0.40) | EPHX2ALDH1A1LMNASMN1; SMN2POLB | |
| SCHEMBL8311013 | 0.92 | EPHX2 (0.44) | EPHX2ALDH1A1DRD2DRD3FKBP1A | |
| SCHEMBL6984619 | 0.87 | LMNA (0.42) | ALDH1A1DRD2LMNASMN1; SMN2 | |
| SCHEMBL6983077 | 0.85 | SOS1 (0.39) | MEN1KMT2ATPSAB1 | |
| Hydrochloric Acid SCHEMBL6984600 | 0.85 | TPSAB1 (0.33) | EPHX2TPSAB1 | |
| Hydrochloric Acid SCHEMBL6983934 | 0.84 | SOS1 (0.39) | MEN1KMT2ATPSAB1 | |
| SCHEMBL8311005 | 0.84 | EPHX2 (0.45) | EPHX2ALDH1A1DRD2DRD3FKBP1A | |
| SCHEMBL6983768 | 0.83 | ACHE (0.35) | TPSAB1 | |
| Hydrochloric Acid SCHEMBL6976629 | 0.82 | ACHE (0.35) | TPSAB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0923575-B1 | CYCLIC ETHER COMPOUNDS AS SODIUM CHANNEL MODULATORS | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-03-12 | — | — | EP | disclosed |
| US-6172085-B1 | CENTRAL NERVOUS SYSTEM AND PSYCHOLOGICAL DISORDERS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-01-09 | — | — | US | disclosed |