⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6725545 | 0.83 | TSHR (0.31) | — | |
| SCHEMBL14693780 | 0.80 | ALDH1A1 (0.33) | — | |
| SCHEMBL1232896 | 0.78 | TSHR (0.48) | — | |
| SCHEMBL6725548 | 0.78 | MMP1 (0.34) | — | |
| SCHEMBL1698005 | 0.78 | TSHR (0.48) | — | |
| SCHEMBL12412835 | 0.76 | MEN1 (0.36) | — | |
| SCHEMBL12863865 | 0.76 | ALOX15 (0.31) | — | |
| SCHEMBL6721191 | 0.76 | — | — | |
| SCHEMBL15438050 | 0.76 | MGAM (0.39) | — | |
| SCHEMBL12863899 | 0.76 | SMN1; SMN2 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934938-B1 | SUBSTITUTED BENZOYLAMINOTHIAZOLE DERIVATIVES AND DRUGS CONTAINING THE SAME | ZERIA PHARM CO LTD (JP) | 2003-01-15 | — | — | EP | disclosed |
| EP-0934938-A1 | SUBSTITUTED BENZOYLAMINOTHIAZOLE DERIVATIVES AND DRUGS CONTAINING THE SAME | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1999-08-11 | — | — | EP | disclosed |