Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.37 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6981558 | 0.92 | NR3C1 (0.37) | KMT2AMEN1MAPTSMN1; SMN2NOTUM | |
| SCHEMBL6978185 | 0.79 | ALDH1A1 (0.51) | KMT2AMEN1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL6981262 | 0.78 | NR3C1 (0.53) | KMT2AMEN1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL6982230 | 0.78 | NR3C1 (0.47) | MAPTSMN1; SMN2ALDH1A1LMNAHPGD | |
| SCHEMBL6979171 | 0.77 | USP2 (0.41) | MAPK1ALDH1A1LMNAHPGDNPSR1 | |
| SCHEMBL7960542 | 0.76 | F2 (0.41) | NPC1MAPTMAPK1RAB9ASMN1; SMN2 | |
| SCHEMBL6984100 | 0.76 | TP53 (0.41) | KMT2AMEN1NPC1MAPTMAPK1 | |
| Hydrochloric Acid SCHEMBL6985379 | 0.74 | ALDH1A1 (0.42) | NPC1MAPTMAPK1RAB9ASMN1; SMN2 | |
| SCHEMBL6987762 | 0.73 | BRD4 (0.48) | MAPTSMN1; SMN2ALDH1A1LMNAHPGD | |
| SCHEMBL6985425 | 0.73 | NR3C1 (0.52) | KMT2AMEN1MAPTSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991624-B1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA (DE) | 2003-11-19 | — | — | EP | disclosed |