Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | AVPR2 | P30518 | 2/20 | 0.35 |
| ▸ | OXTR | P30559 | 1/20 | 0.35 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6980893 | 0.92 | KMT2A (0.40) | NR3C1MAPTLMNAAVPR2MEN1 | |
| SCHEMBL6984049 | 0.82 | NR3C1 (0.52) | NR3C1MAPTLMNAMEN1KMT2A | |
| SCHEMBL6984844 | 0.79 | USP2 (0.39) | NR3C1MAPTLMNAADRB2ADRB1 | |
| SCHEMBL6978185 | 0.76 | ALDH1A1 (0.51) | NR3C1MAPTLMNAMEN1KMT2A | |
| SCHEMBL6982230 | 0.74 | NR3C1 (0.47) | NR3C1MAPTLMNAALDH1A1HPGD | |
| SCHEMBL6984183 | 0.74 | F2 (0.40) | NR3C1POLBTP53ALDH1A1SMN1; SMN2 | |
| SCHEMBL7960542 | 0.73 | F2 (0.41) | MAPTAVPR2OXTRAVPR1APOLB | |
| SCHEMBL6984100 | 0.72 | TP53 (0.41) | MAPTLMNAAVPR2MEN1KMT2A | |
| SCHEMBL6981262 | 0.71 | NR3C1 (0.53) | NR3C1MAPTLMNAMEN1KMT2A | |
| SCHEMBL6985425 | 0.70 | NR3C1 (0.52) | NR3C1MAPTLMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991624-B1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA (DE) | 2003-11-19 | — | — | EP | disclosed |
| US-6300342-B1 | FOR THERAPY OR INHIBITING THROMBUS FORMATION; FOR THERAPY OF FIBRIN-DEPENDENT INFLAMMATORY CONDITION | BOEHRINGER INGELHEIM PHARM KG (DE) | 2001-10-09 | — | — | US | disclosed |