⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6985990 | 0.94 | — | — | |
| SCHEMBL6982865 | 0.85 | HAVCR2 (0.30) | — | |
| SCHEMBL7798949 | 0.77 | KMT2A (0.39) | — | |
| SCHEMBL6984342 | 0.66 | GABRP (0.33) | — | |
| SCHEMBL11705770 | 0.65 | KMT2A (0.52) | — | |
| SCHEMBL8123989 | 0.65 | POLB (0.51) | — | |
| SCHEMBL11704307 | 0.64 | HNF4A (0.45) | — | |
| SCHEMBL11709200 | 0.62 | NQO1 (0.36) | — | |
| SCHEMBL6985233 | 0.62 | RELA (0.39) | — | |
| SCHEMBL11706872 | 0.62 | POLB (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1027351-B1 | PHENANTHROLINE DERIVATIVES | FIBROGEN INC (US) | 2003-12-03 | — | — | EP | claimed |
| EP-1027351-B1 | PHENANTHROLINE DERIVATIVES | FIBROGEN INC (US) | 2003-12-03 | — | — | EP | disclosed |
| US-20010001101-A1 | Phenanthroline derivatives | ZENECA LIMITED | 2001-05-10 | — | — | US | disclosed |
| US-6200974-B1 | FOR PRODUCING AN ANTI-FIBROPROLIFERATIVE EFFECT | ZENECA LIMITED (GB) | 2001-03-13 | — | — | US | disclosed |