Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 7/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL663633 | 0.92 | DGAT1 (0.48) | DGAT1HRH3LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL10185794 | 0.92 | DGAT1 (0.48) | DGAT1HRH3LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL663632 | 0.92 | DGAT1 (0.48) | DGAT1HRH3LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL10184403 | 0.85 | DGAT1 (0.54) | DGAT1HRH3LMNAOPRM1OPRD1 | |
| SCHEMBL10184962 | 0.84 | DGAT1 (0.46) | DGAT1HRH3ALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL10186408 | 0.84 | ALDH1A1 (0.50) | DGAT1HRH3LMNAOPRM1OPRD1 | |
| SCHEMBL10185436 | 0.82 | DGAT1 (0.46) | DGAT1HRH3ALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL16527718 | 0.82 | DGAT1 (0.43) | DGAT1FAAHEPHX2 | |
| SCHEMBL16527717 | 0.82 | DGAT1 (0.43) | DGAT1FAAHEPHX2 | |
| SCHEMBL17694431 | 0.82 | DGAT1 (0.43) | DGAT1FAAHEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2423182-A1 | DIACYLETHYLENEDIAMINE COMPOUND | Astellas Pharma Inc. (JP) | 2012-02-29 | — | — | EP | disclosed |