Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 12/20 | 0.70 |
| ▸ | MEN1 | O00255 | 1/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.70 |
| ▸ | MAPT | P10636 | 1/20 | 0.64 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.57 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.54 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6973290 | 0.92 | EPHX1 (0.61) | MGLLMEN1KMT2AEPHX2HSD11B1 | |
| SCHEMBL6969542 | 0.84 | MGLL (0.62) | MGLLMEN1KMT2AMAPTEPHX2 | |
| SCHEMBL6976855 | 0.84 | GAA (0.67) | MGLLKMT2AEPHX2HSD11B1 | |
| SCHEMBL6208966 | 0.82 | MGLL (1.00) | MGLLMEN1KMT2AMAPTHSD11B1 | |
| SCHEMBL1720910 | 0.82 | MGLL (1.00) | MGLLMEN1KMT2AMAPTHSD11B1 | |
| SCHEMBL19806639 | 0.80 | ERCC5 (0.55) | MEN1KMT2AMAPTEPHX1 | |
| SCHEMBL11396437 | 0.80 | MGLL (0.62) | MGLLMEN1KMT2AMAPT | |
| SCHEMBL1534281 | 0.79 | MAPT (1.00) | MGLLMEN1KMT2AMAPTEPHX2 | |
| SCHEMBL1720091 | 0.77 | MGLL (0.84) | MGLLMEN1KMT2AMAPTHSD11B1 | |
| SCHEMBL1720318 | 0.77 | MGLL (0.70) | MGLLMEN1KMT2AMAPTHSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0892795-B1 | PIPERIDINYLPYRAMIDINE DERIVATIVES | SUMITOMO PHARMA (JP) | 2003-01-08 | — | — | EP | disclosed |
| EP-0892795-A1 | PIPERIDINYLPYRAMIDINE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1999-01-27 | — | — | EP | disclosed |
| WO-1997038992-A1 | PIPERIDINYLPYRAMIDINE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1997-10-23 | — | — | WO | disclosed |