Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.61 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.60 |
| ▸ | ACHE | P22303 | 1/20 | 0.58 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.57 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | MGLL | Q99685 | 2/20 | 0.56 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.56 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | HTR1A | P08908 | 1/20 | 0.52 |
| ▸ | HTR1B | P28222 | 1/20 | 0.52 |
| ▸ | HTR2A | P28223 | 1/20 | 0.52 |
| ▸ | HTR2C | P28335 | 1/20 | 0.52 |
| ▸ | HTR2B | P41595 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6981291 | 0.92 | MGLL (0.70) | EPHX1EPHX2MEN1KMT2AMGLL | |
| SCHEMBL6976855 | 0.89 | GAA (0.67) | EPHX2ACHEALDH1A1KMT2AMGLL | |
| SCHEMBL4251157 | 0.84 | MEN1 (0.61) | PTPN1ALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL9722483 | 0.84 | MEN1 (0.61) | PTPN1ALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL24663619 | 0.83 | ACHE (0.64) | EPHX1EPHX2ACHEPTPN2PTPN1 | |
| SCHEMBL7499151 | 0.83 | ACHE (0.59) | EPHX1EPHX2ACHEPTPN2PTPN1 | |
| SCHEMBL6972961 | 0.81 | KMT2A (0.55) | EPHX1EPHX2ACHEPTPN2PTPN1 | |
| SCHEMBL1673861 | 0.80 | MAPT (0.73) | EPHX1EPHX2ACHEPTPN2PTPN1 | |
| SCHEMBL11788960 | 0.80 | HPGD (0.57) | EPHX2PTPN1ALDH1A1MEN1KMT2A | |
| SCHEMBL17875071 | 0.80 | EPHX1 (0.78) | EPHX1EPHX2ACHEPTPN2PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0892795-B1 | PIPERIDINYLPYRAMIDINE DERIVATIVES | SUMITOMO PHARMA (JP) | 2003-01-08 | — | — | EP | disclosed |
| EP-0892795-A1 | PIPERIDINYLPYRAMIDINE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1999-01-27 | — | — | EP | disclosed |
| WO-1997038992-A1 | PIPERIDINYLPYRAMIDINE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1997-10-23 | — | — | WO | disclosed |