Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 10/20 | 0.39 |
| ▸ | NPC1 | O15118 | 8/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29037875 | 0.80 | POLB (0.47) | LMNAHPGDRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL6469994 | 0.78 | RAB9A (0.49) | LMNARAB9ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL1247110 | 0.76 | TDP1 (0.40) | HPGDRAB9ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL18905 | 0.74 | POLB (0.55) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL19025916 | 0.72 | CYP1A2 (0.48) | LMNAHPGDRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL1724293 | 0.72 | ELANE (0.35) | LMNAHPGDRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL24245 | 0.71 | APP (0.35) | RAB9ANPC1SMN1; SMN2CYP3A4 | |
| SCHEMBL17438680 | 0.70 | S100A4 (0.38) | LMNAHPGDRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL29177611 | 0.70 | RXFP1 (0.60) | LMNARAB9ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL17438712 | 0.69 | RAB9A (0.47) | LMNAHPGDRAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0771565-B1 | Angiogenesis inhibitor | SENJU PHARMA CO (JP) | 2003-01-02 | — | — | EP | claimed |