Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.54 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.54 |
| ▸ | NR3C1 | P04150 | 8/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | TP53 | P04637 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6982229 | 0.91 | NR3C1 (0.60) | NR3C1SMN1; SMN2MAPTTP53LMNA | |
| SCHEMBL6977840 | 0.90 | NR3C1 (0.53) | BRD4CREBBPNR3C1SMN1; SMN2MAPT | |
| SCHEMBL6982759 | 0.90 | BRD4 (0.53) | BRD4CREBBPNR3C1SMN1; SMN2MAPT | |
| Hydrochloric Acid SCHEMBL6986046 | 0.89 | NR3C1 (0.52) | BRD4CREBBPNR3C1SMN1; SMN2MAPT | |
| SCHEMBL6981550 | 0.82 | BRD4 (0.57) | BRD4CREBBPNR3C1SMN1; SMN2MAPT | |
| SCHEMBL6982493 | 0.82 | NR3C1 (0.50) | BRD4CREBBPNR3C1SMN1; SMN2 | |
| SCHEMBL6984828 | 0.81 | NR3C1 (0.56) | BRD4CREBBPNR3C1SMN1; SMN2KMT2A | |
| SCHEMBL6981764 | 0.81 | METAP2 (0.42) | SMN1; SMN2MAPTLMNAKMT2AMEN1 | |
| SCHEMBL6985746 | 0.81 | KMT2A (0.56) | BRD4CREBBPNR3C1SMN1; SMN2MAPT | |
| SCHEMBL6985865 | 0.81 | MAPT (0.56) | NR3C1SMN1; SMN2MAPTTP53LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1228058-B1 | BENZOPYRANYL GUANIDINE DERIVATIVES, PROCESS FOR PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DONGBU HANNONG CHEMICAL CO LTD (KR) | 2003-12-10 | — | — | EP | disclosed |
| EP-0991624-B1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA (DE) | 2003-11-19 | — | — | EP | disclosed |
| US-6300342-B1 | FOR THERAPY OR INHIBITING THROMBUS FORMATION; FOR THERAPY OF FIBRIN-DEPENDENT INFLAMMATORY CONDITION | BOEHRINGER INGELHEIM PHARM KG (DE) | 2001-10-09 | — | — | US | disclosed |
| EP-0991624-A1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | Boehringer Ingelheim Pharma KG (DE) | 2000-04-12 | — | — | EP | disclosed |
| WO-1999000371-A1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA KG (DE) | 1999-01-07 | — | — | WO | disclosed |