Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.68 |
| ▸ | MAPT | P10636 | 3/20 | 0.68 |
| ▸ | MEN1 | O00255 | 3/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.68 |
| ▸ | TSHR | P16473 | 1/20 | 0.68 |
| ▸ | GFER | P55789 | 1/20 | 0.68 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.67 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.67 |
| ▸ | KIF11 | P52732 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | ACHE | P22303 | 3/20 | 0.53 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17461848 | 0.92 | KIF11 (0.67) | ALDH1A1KDM4EHSD17B10MAPTMEN1 | |
| SCHEMBL30366673 | 0.86 | KIF11 (0.74) | ALDH1A1KDM4EHSD17B10MAPTMEN1 | |
| SCHEMBL31506909 | 0.86 | KIF11 (0.74) | ALDH1A1KDM4EHSD17B10MAPTMEN1 | |
| SCHEMBL2333579 | 0.86 | KIF11 (0.74) | ALDH1A1KDM4EHSD17B10MAPTMEN1 | |
| SCHEMBL19331068 | 0.86 | KDM4E (0.66) | ALDH1A1KDM4EHSD17B10MAPTMEN1 | |
| SCHEMBL29373898 | 0.86 | KDM4E (0.66) | ALDH1A1KDM4EHSD17B10MAPTMEN1 | |
| SCHEMBL2597652 | 0.82 | ALDH1A1 (1.00) | ALDH1A1KDM4EHSD17B10MAPTMEN1 | |
| SCHEMBL29391519 | 0.82 | ALDH1A1 (1.00) | ALDH1A1KDM4EHSD17B10MAPTMEN1 | |
| SCHEMBL541732 | 0.81 | ALDH1A1 (0.71) | ALDH1A1KDM4EHSD17B10MAPTMEN1 | |
| Clausine C SCHEMBL601713 | 0.79 | KIF11 (0.67) | ALDH1A1KDM4EHSD17B10MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0985671-B1 | PYRIDOCARBAZOLE DERIVATIVES HAVING cGMP-PDE INHIBITORY EFFECT | MOCHIDA PHARM CO LTD (JP) | 2003-04-02 | — | — | EP | disclosed |
| US-6197768-B1 | THERAPY, PREVENTION ISCHEMIC HEART DISEASE | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2001-03-06 | — | — | US | disclosed |
| EP-0985671-A1 | PYRIDOCARBAZOLE DERIVATIVES HAVING cGMP-PDE INHIBITORY EFFECT | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2000-03-15 | — | — | EP | disclosed |
| US-6018046-A | SELECTIVE ACTION IN INHIBITING CYCLIC GMP-PHOSPHODIESTERASE (CGMP-PDE); PHARMACEUTICALS FOR TREATING DISEASES AGAINST WHICH THE INHIBITORY ACTION IS EFFECTIVE, SUCH AS PULMONARY HYPERTENSION | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2000-01-25 | — | — | US | disclosed |