Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.39 |
| ▸ | PTGES | O14684 | 3/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | F2RL1 | P55085 | 2/20 | 0.30 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.30 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.30 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.30 |
| ▸ | BRAF | P15056 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL697814 | 0.85 | RAB9A (0.46) | KMT2ARAB9ANPC1NISCHPTGES | |
| SCHEMBL705111 | 0.85 | KMT2A (0.48) | KMT2ARAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL697121 | 0.82 | TYK2 (0.43) | KMT2ARAB9ANPC1P2RX7LMNA | |
| SCHEMBL697919 | 0.77 | NPC1 (0.44) | KMT2ARAB9ANPC1NISCHALDH1A1 | |
| SCHEMBL698190 | 0.77 | KMT2A (0.52) | KMT2ARAB9ANPC1NISCHP2RX7 | |
| SCHEMBL697561 | 0.76 | KMT2A (0.44) | KMT2ARAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL712135 | 0.74 | NPC1 (0.65) | KMT2ARAB9ANPC1NISCHALDH1A1 | |
| SCHEMBL697587 | 0.74 | KMT2A (0.42) | KMT2ARAB9ANPC1ALDH1A1KDM4E | |
| SCHEMBL697433 | 0.73 | NPC1 (0.44) | KMT2ARAB9ANPC1ALDH1A1HPGD | |
| SCHEMBL698900 | 0.73 | KMT2A (0.46) | KMT2ARAB9ANPC1NISCHP2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2423199-A1 | Substituted imidazoles and their use as pesticides | Pfizer Limited (GB) | 2012-02-29 | — | — | EP | disclosed |
| CN-101370786-B | Substituted imidazoles and their use as pesticides | PFIZER | 2012-01-11 | — | — | CN | disclosed |
| EP-1981853-B1 | SUBSTITUTED IMIDAZOLES AND THEIR USE AS PESTICIDES | PFIZER LTD (GB) | 2011-04-13 | — | — | EP | disclosed |