Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | JAK1 | P23458 | 1/20 | 0.37 |
| ▸ | TYK2 | P29597 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | ALPL | P05186 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL705111 | 0.88 | KMT2A (0.48) | KMT2ARAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL11304735 | 0.82 | KMT2A (0.47) | KMT2ARAB9ANPC1MEN1SMN1; SMN2 | |
| SCHEMBL1573101 | 0.81 | TYK2 (0.43) | KMT2ARAB9ANPC1MEN1LMNA | |
| SCHEMBL11267970 | 0.80 | AKR1C4 (0.41) | KMT2ARAB9ANPC1MEN1SMN1; SMN2 | |
| SCHEMBL11141785 | 0.79 | KMT2A (0.46) | KMT2ARAB9ANPC1MEN1SMN1; SMN2 | |
| SCHEMBL6087751 | 0.76 | FABP3 (0.48) | KMT2AMEN1SMN1; SMN2TSHRLMNA | |
| SCHEMBL698190 | 0.76 | KMT2A (0.52) | KMT2ARAB9ANPC1MEN1SMN1; SMN2 | |
| SCHEMBL702086 | 0.76 | KMT2A (0.46) | KMT2ARAB9ANPC1MEN1SMN1; SMN2 | |
| SCHEMBL696873 | 0.75 | KMT2A (0.55) | KMT2ARAB9ANPC1SMN1; SMN2TSHR | |
| SCHEMBL696226 | 0.75 | KMT2A (0.41) | KMT2ARAB9ANPC1MEN1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2423199-A1 | Substituted imidazoles and their use as pesticides | Pfizer Limited (GB) | 2012-02-29 | — | — | EP | disclosed |
| EP-1981853-B1 | SUBSTITUTED IMIDAZOLES AND THEIR USE AS PESTICIDES | PFIZER LTD (GB) | 2011-04-13 | — | — | EP | disclosed |
| EP-0048827-A1 | Substituted 2,4-dichlorophenyl-imidazolyl-vinyl ketones, processes for their preparation and antimicrobial agents containing these compounds | BAYER AG (DE) | 1982-04-07 | — | — | EP | disclosed |