Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DCUN1D1 | Q96GG9 | 10/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 1.00 |
| ▸ | APOBEC3G | Q9HC16 | 3/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 1.00 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.64 |
| ▸ | GAA | P10253 | 3/20 | 0.62 |
| ▸ | HPGD | P15428 | 3/20 | 0.62 |
| ▸ | MPI | P34949 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | GFER | P55789 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.47 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | ALPL | P05186 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28371630 | 0.73 | DCUN1D1 (1.00) | DCUN1D1ALDH1A1KDM4EAPOBEC3GTDP1 | |
| SCHEMBL7688464 | 0.71 | DCUN1D1 (1.00) | DCUN1D1ALDH1A1KDM4EAPOBEC3GTDP1 | |
| SCHEMBL10944351 | 0.65 | NR1H2 (0.77) | DCUN1D1ALDH1A1KDM4EAPOBEC3GTDP1 | |
| SCHEMBL416830 | 0.65 | MGAM (0.49) | DCUN1D1ALDH1A1KDM4EAPOBEC3GTDP1 | |
| SCHEMBL29802156 | 0.65 | CYP2A6 (0.67) | DCUN1D1ALDH1A1KDM4EAPOBEC3GTDP1 | |
| SCHEMBL671133 | 0.65 | CYP2A6 (0.67) | DCUN1D1ALDH1A1KDM4EAPOBEC3GTDP1 | |
| SCHEMBL29883244 | 0.65 | CYP2A6 (0.67) | DCUN1D1ALDH1A1KDM4EAPOBEC3GTDP1 | |
| SCHEMBL18015441 | 0.65 | LDHA (0.54) | DCUN1D1ALDH1A1KDM4EAPOBEC3GTDP1 | |
| SCHEMBL15798384 | 0.65 | ALDH1A1 (0.47) | DCUN1D1ALDH1A1KDM4EAPOBEC3GTDP1 | |
| SCHEMBL23758280 | 0.64 | MGAM (0.55) | DCUN1D1ALDH1A1KDM4EAPOBEC3GTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1109790-B1 | 1, 2, 4-TRIAZOLE-3-THIONE COMPOUNDS | ASTRAZENECA AB (SE) | 2003-05-14 | — | — | EP | disclosed |
| EP-1109790-A1 | 1, 2, 4-TRIAZOLE-3-THIONE COMPOUNDS | AstraZeneca AB (SE) | 2001-06-27 | — | — | EP | disclosed |
| WO-2000012489-A1 | 1, 2, 4-TRIAZOLE-3-THIONE COMPOUNDS | ASTRAZENECA AB (SE) | 2000-03-09 | — | — | WO | disclosed |