Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 12/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | DHODH | Q02127 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 2/20 | 0.39 |
| ▸ | METAP2 | P50579 | 1/20 | 0.39 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8081766 | 0.78 | NUDT1 (0.59) | CNR2CNR1DHODHMETAP2NUDT1 | |
| SCHEMBL1170898 | 0.78 | DHODH (0.54) | CNR2CNR1DHODHPARP1 | |
| SCHEMBL11767146 | 0.77 | MAOB (0.70) | CNR2CNR1MAOBADORA2AADORA2B | |
| SCHEMBL31027957 | 0.76 | DHODH (0.59) | CNR2DHODHPARP1 | |
| SCHEMBL11705160 | 0.75 | MAOB (0.63) | CNR2CNR1MAOBADORA2AADORA2B | |
| SCHEMBL6984307 | 0.75 | MGAM (0.49) | — | |
| SCHEMBL2010618 | 0.75 | CNR2 (0.48) | CNR2CNR1DHODHNPY5RPARP1 | |
| SCHEMBL7146754 | 0.75 | DHODH (0.62) | CNR2DHODHPARP1 | |
| SCHEMBL21855798 | 0.75 | ADORA1 (0.56) | MAOBADORA2AADORA2BADORA1PARP1 | |
| SCHEMBL9306889 | 0.75 | NPC1 (0.50) | CNR2CNR1DHODHNPY5RMETAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1286987-A1 | HETEROCYCLIC HYDRAZONES FOR USE AS ANTI-CANCER AGENTS | Austria Wirtschaftsservice Gesellschaft mit beschränkter Haftung (AT) | 2003-03-05 | — | — | EP | disclosed |
| WO-2001094340-A1 | HETEROCYCLIC HYDRAZONES FOR USE AS ANTI-CANCER AGENTS | INNOVATIONSAGENTUR GESELLSCHAFT M.B.H. (AT) | 2001-12-13 | — | — | WO | disclosed |