SCHEMBL2010618

SCHEMBL2010618

Sc1nc2c(-c3ccccc3)cccc2[nH]1

nearest known ligand 0.48

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 12/20 0.48
CNR1 P21554 1/20 0.43
METAP2 P50579 1/20 0.42
DHODH Q02127 3/20 0.42
NPY5R Q15761 1/20 0.41
PIK3CD O00329 1/20 0.39
PIK3CA P42336 1/20 0.39
PIK3CB P42338 1/20 0.39
PARP1 P09874 1/20 0.39
PLK4 O00444 1/20 0.39
MAPK9 P45984 1/20 0.39
LIMK1 P53667 1/20 0.39
CLK4 Q9HAZ1 1/20 0.39
AKT3 Q9Y243 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1170898 0.81 DHODH (0.54) CNR2CNR1DHODHPARP1
SCHEMBL12814432 0.81 PARP1 (0.46) PARP1
SCHEMBL31027957 0.80 DHODH (0.59) CNR2DHODHPARP1
SCHEMBL8081766 0.79 NUDT1 (0.59) CNR2CNR1METAP2DHODH
SCHEMBL9306889 0.79 NPC1 (0.50) CNR2CNR1METAP2DHODHNPY5R
SCHEMBL7146754 0.79 DHODH (0.62) CNR2DHODHPARP1
SCHEMBL10696507 0.79 CNR2 (0.49) CNR2CNR1DHODHPARP1
SCHEMBL230979 0.77 DHODH (0.53) CNR2DHODHPARP1
SCHEMBL4457030 0.77 DHODH (0.53) CNR2DHODHPARP1
SCHEMBL1830191 0.76 DHODH (0.51) CNR2DHODHPARP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109566351-B Culture medium for improving germination rate 上海派布利克贸易有限公司 2021-10-26 CN disclosed
CN-109566374-B High-yield pea seedling and planting method thereof 刘斌 2021-04-06 CN disclosed
EP-2550554-A1 BLACK CURABLE COMPOSITION, LIGHT-SHIELDING COLOR FILTER FOR A SOLID-STATE IMAGING DEVICE AND METHOD OF PRODUCING THE SAME, SOLID-STATE IMAGING DEVICE, WAFER LEVEL LENS, AND CAMERA MODULE FUJIFILM Corporation (JP) 2013-01-30 EP disclosed
EP-2510399-A1 BLACK CURABLE COMPOSITION, LIGHT-SHIELDING COLOR FILTER, LIGHT-SHIELDING FILM AND METHOD FOR MANUFACTURING THE SAME, WAFER LEVEL LENS, AND SOLID-STATE IMAGING DEVICE FUJIFILM Corporation (JP) 2012-10-17 EP disclosed
WO-2011118850-A1 BLACK CURABLE COMPOSITION, LIGHT-SHIELDING COLOR FILTER FOR A SOLID-STATE IMAGING DEVICE AND METHOD OF PRODUCING THE SAME, SOLID-STATE IMAGING DEVICE, WAFER LEVEL LENS, AND CAMERA MODULE FUJIFILM CORPORATION (JP) 2011-09-29 WO disclosed
WO-2011071133-A1 BLACK CURABLE COMPOSITION, LIGHT-SHIELDING COLOR FILTER, LIGHT-SHIELDING FILM AND METHOD FOR MANUFACTURING THE SAME, WAFER LEVEL LENS, AND SOLID-STATE IMAGING DEVICE FUJIFILM CORPORATION (JP) 2011-06-16 WO disclosed
US-5347008-A Thio(cyclo) alkanepolycarboxylic acids containing heterocyclic substituents CIBA-GEIGY CORPORATION (US) 1994-09-13 US disclosed
EP-0161220-B1 PROCESS FOR THE PREPARATION OF BETA-(BENZOTHIAZOLYLTHIO) AND BETA (BENZIMIDAZOLYLTHIO)CARBOXYLIC-ACID DERIVATIVES CIBA-GEIGY AG (CH) 1991-08-14 EP disclosed
US-4652653-A Process for the preparation of β-(benzothiazolylthio)- and β-(benzimidazolylthio)-carboxylic acid derivatives CIBA-GEIGY CORPORATION (US) 1987-03-24 US disclosed
US-4612378-A Process for the preparation of β-(benzothiazolylthio)- and β-(benzimidazolylthio-carboxylic acids CIBA-GEIGY CORPORATION (US) 1986-09-16 US disclosed
EP-0161220-A2 Process for the preparation of beta-(benzothiazolylthio) and beta (benzimidazolylthio)carboxylic-acid derivatives CIBA-GEIGY AG (CH) 1985-11-13 EP disclosed
EP-0129506-A2 Heterocyclically substituted thio(cyclo)alkane polycarboxylic acids CIBA-GEIGY AG (CH) 1984-12-27 EP disclosed
EP-0126030-A2 Process for the preparation of beta-(benzothiazolylthio) and beta-(benzimidazolylthio) carboxylic acids CIBA-GEIGY AG (CH) 1984-11-21 EP disclosed