Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 3/20 | 0.40 |
| ▸ | GHSR | Q92847 | 4/20 | 0.36 |
| ▸ | FAAH | O00519 | 2/20 | 0.35 |
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
| ▸ | DRD3 | P35462 | 2/20 | 0.33 |
| ▸ | CDK1 | P06493 | 2/20 | 0.33 |
| ▸ | KDR | P35968 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SCD | O00767 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.32 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.32 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6988687 | 0.89 | LMNA (0.45) | MAPK14GHSRFAAHP2RX7LMNA | |
| SCHEMBL6986755 | 0.86 | MAPK14 (0.39) | MAPK14GHSRFAAHDRD2DRD3 | |
| SCHEMBL6984410 | 0.84 | MAPK14 (0.39) | MAPK14GHSRFAAHDRD2DRD3 | |
| SCHEMBL6987898 | 0.78 | MAPK14 (0.38) | MAPK14GHSRKDM4ESCD | |
| SCHEMBL6986945 | 0.78 | F10 (0.53) | MAPK14GHSRKDM4EALDH1A1MAPT | |
| SCHEMBL6982897 | 0.77 | KDM4E (0.42) | MAPK14GHSRKDM4ESCD | |
| Hydrochloric Acid SCHEMBL6985167 | 0.77 | F10 (0.53) | MAPK14GHSRKDM4EALDH1A1MAPT | |
| SCHEMBL6982128 | 0.76 | SCD (0.42) | MAPTSCD | |
| Hydrochloric Acid SCHEMBL6985678 | 0.76 | SCD (0.42) | MAPTSCD | |
| SCHEMBL6988459 | 0.74 | MAPK14 (0.41) | MAPK14GHSRFAAHKDM4EP2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1289972-A1 | SERINE PROTEASE INHIBITORS | ELI LILLY AND COMPANY (US) | 2003-03-12 | — | — | EP | disclosed |
| WO-2001096323-A1 | SERINE PROTEASE INHIBITORS | ELI LILLY AND COMPANY (US) | 2001-12-20 | — | — | WO | disclosed |