Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | GAA | P10253 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4454162 | 0.94 | LMNA (0.55) | ELANEMAPTGAAALDH1A1HSP90AA1 | |
| SCHEMBL4454157 | 0.94 | LMNA (0.55) | ELANEMAPTGAAALDH1A1HSP90AA1 | |
| SCHEMBL4454166 | 0.94 | LMNA (0.55) | ELANEMAPTGAAALDH1A1HSP90AA1 | |
| SCHEMBL918946 | 0.86 | LMNA (0.50) | ELANEMAPTGAAALDH1A1HSP90AA1 | |
| SCHEMBL7410333 | 0.83 | ELANE (0.50) | ELANEMAPTGAAALDH1A1HSP90AA1 | |
| SCHEMBL8913760 | 0.78 | ELANE (0.53) | ELANEMAPTGAAALDH1A1HSP90AA1 | |
| SCHEMBL8846112 | 0.78 | ELANE (0.53) | ELANEMAPTGAAALDH1A1HSP90AA1 | |
| SCHEMBL8913776 | 0.78 | ELANE (0.53) | ELANEMAPTGAAALDH1A1HSP90AA1 | |
| SCHEMBL8846101 | 0.78 | ELANE (0.53) | ELANEMAPTGAAALDH1A1HSP90AA1 | |
| SCHEMBL8846105 | 0.78 | ELANE (0.53) | ELANEMAPTGAAALDH1A1HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0724569-B1 | PROCESS FOR THE PREPARATION OF AN OXIRANE, AZIRIDINE OR CYCLOPROPANE | AVECIA LTD (GB) | 2003-03-12 | — | — | EP | disclosed |
| US-5703246-A | REACTING AN ORGANOMETALLIC COMPOUND WITH ORGANOSULFUR COMPOUND | ZENECA LIMITED (GB) | 1997-12-30 | — | — | US | disclosed |
| EP-0724569-A1 | PROCESS FOR THE PREPARATION OF AN OXIRANE, AZIRIDINE OR CYCLOPROPANE | ZENECA LIMITED (GB) | 1996-08-07 | — | — | EP | disclosed |
| WO-1995011230-A1 | PROCESS FOR THE PREPARATION OF AN OXIRANE, AZIRIDINE OR CYCLOPROPANE | ZENECA LIMITED (GB) | 1995-04-27 | — | — | WO | disclosed |