Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | TTR | P02766 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6228156 | 0.84 | EDNRA (0.54) | MAPTALDH1A1LMNAHSD17B10TSHR | |
| SCHEMBL7293698 | 0.84 | EDNRA (0.54) | MAPTALDH1A1LMNAHSD17B10TSHR | |
| SCHEMBL6229779 | 0.84 | EDNRA (0.54) | MAPTALDH1A1LMNAHSD17B10TSHR | |
| SCHEMBL7144597 | 0.84 | EDNRA (0.54) | MAPTALDH1A1LMNAHSD17B10TSHR | |
| SCHEMBL9258771 | 0.84 | EDNRA (0.54) | MAPTALDH1A1LMNAHSD17B10TSHR | |
| SCHEMBL4454157 | 0.84 | LMNA (0.55) | ELANEMAPTGAAALDH1A1HSP90AA1 | |
| SCHEMBL4454166 | 0.84 | LMNA (0.55) | ELANEMAPTGAAALDH1A1HSP90AA1 | |
| SCHEMBL4454162 | 0.84 | LMNA (0.55) | ELANEMAPTGAAALDH1A1HSP90AA1 | |
| SCHEMBL8927247 | 0.83 | EDNRA (0.53) | MAPTALDH1A1LMNAHSD17B10TSHR | |
| SCHEMBL6982352 | 0.83 | ELANE (0.58) | ELANEMAPTGAAALDH1A1HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0988297-A2 | PROCESS FOR PREPARING OPTICALLY ACTIVE PHENYLOXIRANE COMPOUNDS | Tanabe Seiyaku Co., Ltd. (JP) | 2000-03-29 | — | — | EP | disclosed |
| WO-1998056762-A2 | PROCESS FOR PREPARING OPTICALLY ACTIVE PHENYLOXIRANE COMPOUNDS | TANABE SEIYAKU CO., LTD. (JP) | 1998-12-17 | — | — | WO | disclosed |
| US-4552695-A | Process for production of diltiazem hydrochloride | SHIONOGI & CO., LTD. (JP) | 1985-11-12 | — | — | US | disclosed |