Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | BCL2 | P10415 | 2/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6986812 | 0.88 | ALDH1A1 (0.40) | SMN1; SMN2TSHRBCL2MDM2MCL1 | |
| SCHEMBL6985846 | 0.87 | BCL2 (0.41) | SMN1; SMN2TSHRBCL2MDM2MCL1 | |
| SCHEMBL6983706 | 0.87 | HTT (0.36) | CYP2C9SMN1; SMN2TSHRHTTALDH1A1 | |
| SCHEMBL6987183 | 0.85 | TSHR (0.45) | SMN1; SMN2TSHRBCL2MDM2MCL1 | |
| SCHEMBL6979346 | 0.85 | ALDH1A1 (0.41) | CYP2C9SMN1; SMN2CYP1A2CYP2C19TSHR | |
| SCHEMBL6987419 | 0.83 | ALDH1A1 (0.43) | SMN1; SMN2TSHRHTTALDH1A1 | |
| SCHEMBL6989950 | 0.82 | CYP3A4 (0.35) | CYP2C9CYP1A2CYP2C19TSHRHTT | |
| SCHEMBL6987971 | 0.81 | HTT (0.38) | SMN1; SMN2TSHRHTTALDH1A1 | |
| SCHEMBL6986605 | 0.81 | HTT (0.48) | SMN1; SMN2TSHRBCL2MDM2MCL1 | |
| SCHEMBL6983312 | 0.81 | HTT (0.37) | SMN1; SMN2TSHRHTTALDH1A1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1313733-A1 | PYRAZOLOPYRIDINE COMPOUND AND PHARMACEUTICAL USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-05-28 | — | — | EP | disclosed |
| WO-2002018382-A1 | PYRAZOLOPYRIDINE COMPOUND AND PHARMACEUTICAL USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-03-07 | — | — | WO | disclosed |