Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6980817 | 0.94 | KCNH2 (0.56) | KCNH2L3MBTL1PKMLMNAKMT2A | |
| SCHEMBL6981760 | 0.88 | KCNH2 (0.54) | KCNH2L3MBTL1PKMLMNAKMT2A | |
| SCHEMBL6583579 | 0.88 | KCNH2 (0.70) | KCNH2L3MBTL1PKMLMNAKMT2A | |
| SCHEMBL6583582 | 0.88 | KCNH2 (0.70) | KCNH2L3MBTL1PKMLMNAKMT2A | |
| SCHEMBL6163980 | 0.83 | KCNH2 (0.47) | KCNH2L3MBTL1PKMLMNAKMT2A | |
| SCHEMBL6978258 | 0.82 | HCAR3 (0.52) | KCNH2KMT2AMEN1MAPK1MAPT | |
| SCHEMBL13951737 | 0.80 | KCNH2 (0.42) | KCNH2PKMLMNAKMT2AMEN1 | |
| SCHEMBL14765557 | 0.80 | KCNH2 (0.42) | KCNH2PKMLMNAKMT2AMEN1 | |
| SCHEMBL12961840 | 0.80 | KCNH2 (0.42) | KCNH2PKMLMNAKMT2AMEN1 | |
| SCHEMBL6161775 | 0.80 | KCNH2 (0.42) | KCNH2PKMLMNAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934296-B1 | CHROMAN DERIVATIVES | NISSAN CHEMICAL IND LTD (JP) | 2003-06-04 | — | — | EP | disclosed |
| US-6066631-A | Chroman derivatives | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2000-05-23 | — | — | US | disclosed |
| EP-0934296-A1 | CHROMAN DERIVATIVES | NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) | 1999-08-11 | — | — | EP | disclosed |
| WO-1998004542-A1 | CHROMAN DERIVATIVES | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1998-02-05 | — | — | WO | disclosed |