Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12961840 | 0.88 | KCNH2 (0.42) | KCNH2LMNAALDH1A1MAPTKMT2A | |
| SCHEMBL6161775 | 0.88 | KCNH2 (0.42) | KCNH2LMNAALDH1A1MAPTKMT2A | |
| SCHEMBL14765557 | 0.88 | KCNH2 (0.42) | KCNH2LMNAALDH1A1MAPTKMT2A | |
| SCHEMBL13951737 | 0.88 | KCNH2 (0.42) | KCNH2LMNAALDH1A1MAPTKMT2A | |
| SCHEMBL6980817 | 0.87 | KCNH2 (0.56) | KCNH2LMNAALDH1A1MAPTKMT2A | |
| SCHEMBL6163946 | 0.86 | KCNH2 (0.44) | KCNH2LMNAALDH1A1MAPTKMT2A | |
| SCHEMBL6982472 | 0.83 | KCNH2 (0.55) | KCNH2LMNAALDH1A1MAPTKMT2A | |
| SCHEMBL9742503 | 0.83 | NPSR1 (0.41) | KCNH2LMNAALDH1A1MAPTKMT2A | |
| SCHEMBL6978258 | 0.83 | HCAR3 (0.52) | KCNH2ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL6583582 | 0.83 | KCNH2 (0.70) | KCNH2LMNAALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1212314-B1 | BENZOPYRAN DERIVATIVE | NISSAN CHEMICAL IND LTD (JP) | 2005-11-30 | — | — | EP | disclosed |
| US-6589983-B1 | Antiarrhythmic agents having the prolongation effect on the functional refractory period as a main function | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2003-07-08 | — | — | US | disclosed |
| EP-1212314-A1 | BENZOPYRAN DERIVATIVE | Nissan Chemical Industries, Ltd. (JP) | 2002-06-12 | — | — | EP | disclosed |
| WO-2001021610-A1 | BENZOPYRAN DERIVATIVE | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2001-03-29 | — | — | WO | disclosed |