Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HTR6 | P50406 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6074092 | 0.86 | ALDH1A1 (0.54) | ALDH1A1MAPTRECQLUSP2GFER | |
| SCHEMBL28751618 | 0.81 | ALDH1A1 (0.56) | ALDH1A1MAPTRECQLUSP2GFER | |
| SCHEMBL6074374 | 0.81 | POLB (0.59) | ALDH1A1MAPTRECQLUSP2GFER | |
| SCHEMBL6073863 | 0.80 | GFER (0.77) | ALDH1A1MAPTRECQLGFERL3MBTL1 | |
| SCHEMBL7163493 | 0.80 | MCOLN3 (0.50) | ALDH1A1MAPTL3MBTL1KMT2ALMNA | |
| SCHEMBL6074446 | 0.79 | LMNA (0.61) | ALDH1A1MAPTRECQLUSP2POLB | |
| SCHEMBL6074068 | 0.79 | CES1 (0.61) | ALDH1A1MAPTRECQLUSP2GFER | |
| SCHEMBL6074611 | 0.76 | MEN1 (0.78) | ALDH1A1MAPTRECQLL3MBTL1POLB | |
| SCHEMBL6074493 | 0.76 | KMT2A (0.75) | ALDH1A1MAPTRECQLUSP2KMT2A | |
| SCHEMBL6074530 | 0.76 | ALDH1A1 (0.52) | ALDH1A1MAPTRECQLUSP2GFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1301482-A1 | CYCLIC AMINE PHENYL BETA-3 ADRENERGIC RECEPTOR AGONISTS | Wyeth (US) | 2003-04-16 | — | — | EP | disclosed |
| WO-2002006232-A1 | CYCLIC AMINE PHENYL BETA-3 ADRENERGIC RECEPTOR AGONISTS | WYETH (US) | 2002-01-24 | — | — | WO | disclosed |