Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCB | P05771 | 7/20 | 0.67 |
| ▸ | PRKCA | P17252 | 6/20 | 0.67 |
| ▸ | CDK4 | P11802 | 4/20 | 0.67 |
| ▸ | CCND1 | P24385 | 4/20 | 0.67 |
| ▸ | CAMK2D | Q13557 | 4/20 | 0.67 |
| ▸ | PRKACA | P17612 | 4/20 | 0.67 |
| ▸ | PRKACG | P22612 | 4/20 | 0.67 |
| ▸ | PRKACB | P22694 | 4/20 | 0.67 |
| ▸ | CDK2 | P24941 | 3/20 | 0.67 |
| ▸ | PRKCH | P24723 | 3/20 | 0.67 |
| ▸ | PRKCE | Q02156 | 3/20 | 0.67 |
| ▸ | PRKCQ | Q04759 | 3/20 | 0.67 |
| ▸ | PRKCD | Q05655 | 3/20 | 0.67 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.67 |
| ▸ | CCNE2 | O96020 | 2/20 | 0.67 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.67 |
| ▸ | ABL1 | P00519 | 2/20 | 0.67 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.67 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.67 |
| ▸ | PRKCG | P05129 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6499673 | 0.83 | PRKCB (0.51) | PRKCBPRKCACDK4CCND1CAMK2D | |
| Ro-316233 SCHEMBL624896 | 0.82 | PRKCB (1.00) | PRKCBPRKCACDK4CCND1CAMK2D | |
| Ro-316233 SCHEMBL29373011 | 0.82 | PRKCB (1.00) | PRKCBPRKCACDK4CCND1CAMK2D | |
| SCHEMBL7815290 | 0.81 | PRKCB (0.60) | PRKCBPRKCACDK4CCND1CAMK2D | |
| SCHEMBL7822950 | 0.79 | PRKCB (0.74) | PRKCBPRKCACDK4CCND1CAMK2D | |
| SCHEMBL7822805 | 0.79 | PRKCB (0.74) | PRKCBPRKCACDK4CCND1CAMK2D | |
| SCHEMBL7824736 | 0.79 | PRKCB (0.74) | PRKCBPRKCACDK4CCND1CAMK2D | |
| SCHEMBL9085236 | 0.79 | PRKCB (0.74) | PRKCBPRKCACDK4CCND1CAMK2D | |
| SCHEMBL9087083 | 0.79 | PRKCB (0.74) | PRKCBPRKCACDK4CCND1CAMK2D | |
| SCHEMBL9085391 | 0.79 | PRKCB (0.74) | PRKCBPRKCACDK4CCND1CAMK2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1283836-A2 | NEUROPROTECTIVE AND ANTI-PROLIFERATIVE COMPOUNDS | Aegera Therapeutics Inc. (CA) | 2003-02-19 | — | — | EP | disclosed |
| WO-2001087887-A2 | NEUROPROTECTIVE AND ANTI-PROLIFERATIVE COMPOUNDS | AEGERA THERAPEUTICS INC. (CA) | 2001-11-22 | — | — | WO | disclosed |