Styrene

Styrene

SCHEMBL6982750

C=C(CCCC)C(=O)O.C=Cc1ccccc1.CCCCC(=CC(=O)O)C(=O)O

nearest known ligand 0.40

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Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 4/20 0.40
PTGES O14684 3/20 0.40
PPARG P37231 2/20 0.40
LMNA P02545 1/20 0.40
TDP1 Q9NUW8 1/20 0.39
CES2 O00748 3/20 0.37
CES1 P23141 3/20 0.37
ALDH1A1 P00352 1/20 0.37
TSHR P16473 1/20 0.37
HDAC3 O15379 1/20 0.36
HTT P42858 1/20 0.35
APEX1 P27695 1/20 0.35
CYP3A4 P08684 1/20 0.34
CYP2C9 P11712 1/20 0.34
EGFR P00533 1/20 0.34
KDM4E B2RXH2 1/20 0.33
MEN1 O00255 1/20 0.33
RECQL P46063 1/20 0.33
KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL27585078 0.95 ALOX5 (0.43) ALOX5PTGESPPARGLMNATDP1
Styrene SCHEMBL17065130 0.89 LMNA (0.47) ALOX5PTGESPPARGLMNATDP1
Styrene SCHEMBL5270544 0.89 LMNA (0.47) ALOX5PTGESPPARGLMNATDP1
Styrene SCHEMBL258132 0.89 LMNA (0.47) ALOX5PTGESPPARGLMNATDP1
Styrene SCHEMBL987788 0.88 LMNA (0.44) ALOX5PTGESPPARGLMNATDP1
Styrene SCHEMBL27486502 0.87 TDP1 (0.46) LMNATDP1CES2CES1HTT
Styrene SCHEMBL4407755 0.86 LMNA (0.43) ALOX5PTGESPPARGLMNATDP1
Styrene SCHEMBL3430407 0.85 LMNA (0.44) ALOX5PTGESPPARGLMNATDP1
Styrene SCHEMBL7783115 0.85 LMNA (0.44) ALOX5PTGESPPARGLMNATDP1
Styrene SCHEMBL1628229 0.84 LMNA (0.54) LMNATDP1CES2CES1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0744672-B1 Image forming apparatus and method employing an intermediate transfer member CANON KK (JP) 2003-01-02 EP disclosed
US-5809373-A Image forming apparatus which back-transfers residual toner from an intermediate transfer member to a photosensitive drum CANON KABUSHIKI KAISHA (JP) 1998-09-15 US disclosed
EP-0744672-A1 Image forming apparatus employing intermediate transfer member CANON KABUSHIKI KAISHA (JP) 1996-11-27 EP disclosed