Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | CTSK | P43235 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6122567 | 0.90 | CTSK (0.45) | ALDH1A1CTSKGAATRPM8POLB | |
| SCHEMBL17388825 | 0.88 | ALDH1A1 (0.43) | ALDH1A1CTSKGAATRPM8POLB | |
| SCHEMBL6121971 | 0.87 | CTSK (0.44) | ALDH1A1CTSKGAATRPM8POLB | |
| SCHEMBL17388824 | 0.87 | ALDH1A1 (0.45) | ALDH1A1CTSKGAATRPM8POLB | |
| SCHEMBL6122977 | 0.87 | TRPM8 (0.46) | ALDH1A1CTSKGAATRPM8POLB | |
| SCHEMBL16762178 | 0.87 | ALDH1A1 (0.46) | ALDH1A1CTSKGAATRPM8POLB | |
| SCHEMBL16762075 | 0.87 | ALDH1A1 (0.46) | ALDH1A1CTSKGAATRPM8POLB | |
| SCHEMBL6123072 | 0.84 | CTSK (0.46) | ALDH1A1CTSKGAATRPM8POLB | |
| SCHEMBL6121764 | 0.84 | CTSK (0.46) | ALDH1A1CTSKGAATRPM8POLB | |
| SCHEMBL6122227 | 0.84 | CTSK (0.47) | ALDH1A1CTSKGAATRPM8POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1071680-A4 | N,N-DISUBSTITUTED AMIDES THAT INHIBIT THE BINDING OF INTEGRINS TO THEIR RECEPTORS | TEXAS BIOTECHNOLOGY CORP (US) | 2003-03-05 | — | — | EP | disclosed |
| EP-1071680-A1 | N,N-DISUBSTITUTED AMIDES THAT INHIBIT THE BINDING OF INTEGRINS TO THEIR RECEPTORS | TEXAS BIOTECHNOLOGY CORPORATION (US) | 2001-01-31 | — | — | EP | disclosed |
| WO-1999052898-A1 | N,N-DISUBSTITUTED AMIDES THAT INHIBIT THE BINDING OF INTEGRINS TO THEIR RECEPTORS | TEXAS BIOTECHNOLOGY CORPORATION (US) | 1999-10-21 | — | — | WO | disclosed |