Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 2/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.60 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.60 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.43 |
| ▸ | DYRK1B | Q9Y463 | 3/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | FYN | P06241 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6989157 | 0.99 | CYP2A6 (0.59) | CYP2A6CYP3A4CYP2C9CYP2E1CYP2B6 | |
| SCHEMBL6985848 | 0.86 | DYRK1A (0.50) | CYP2A6CYP3A4CYP2C9CYP2E1CYP2B6 | |
| SCHEMBL6985095 | 0.83 | CYP11B1 (0.45) | CYP2A6CYP3A4CYP2C9CYP2E1CYP2B6 | |
| Hydrochloric Acid SCHEMBL6985047 | 0.82 | CYP11B1 (0.44) | CYP2A6CYP3A4CYP2C9CYP2E1CYP2B6 | |
| SCHEMBL6987086 | 0.82 | DYRK1A (0.48) | CYP2A6CYP3A4CYP2C9CYP2E1CYP2B6 | |
| SCHEMBL6983734 | 0.82 | CYP2A6 (0.59) | CYP2A6CYP3A4CYP2C9CYP2E1CYP2B6 | |
| SCHEMBL6985680 | 0.81 | CYP19A1 (0.50) | CYP2A6CYP3A4CYP2C9CYP2E1CYP2B6 | |
| Hydrochloric Acid SCHEMBL6981675 | 0.81 | DYRK1A (0.47) | CYP2A6CYP3A4CYP2C9CYP2E1CYP2B6 | |
| Hydrochloric Acid SCHEMBL6986441 | 0.81 | CYP2A6 (0.57) | CYP2A6CYP3A4CYP2C9CYP2E1CYP2B6 | |
| SCHEMBL6981139 | 0.80 | CYP3A4 (0.54) | CYP3A4CYP2C9CYP2B6KDM4EMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030130340-A1 | Novel benzothiophene derivatives | DAIICHI PHARMACEUTICAL CO. LTD. | 2003-07-10 | — | — | US | disclosed |
| EP-1283209-A1 | NOVEL BENZOTHIOPHENE DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2003-02-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030130340-A1 | Novel benzothiophene derivatives | CYP17A1, CYP21A2, HSD17B1 | CYP2A6 110/4885CYP3A4 88/4885CYP2C9 100/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.