Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOS1 | Q07889 | 1/20 | 0.39 |
| ▸ | CCR2 | P41597 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.34 |
| ▸ | BACE1 | P56817 | 2/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.32 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.31 |
| ▸ | MPO | P05164 | 2/20 | 0.31 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.31 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6983934 | 0.99 | SOS1 (0.39) | SOS1CCR2MEN1KMT2AMAPT | |
| SCHEMBL6983768 | 0.87 | ACHE (0.35) | SLC6A4SLC6A3SIGMAR1ACHETPSAB1 | |
| Hydrochloric Acid SCHEMBL6984600 | 0.87 | TPSAB1 (0.33) | CCR2SIGMAR1KCNA3ACHETPSAB1 | |
| Hydrochloric Acid SCHEMBL6976629 | 0.86 | ACHE (0.35) | SLC6A4SLC6A3SIGMAR1ACHETPSAB1 | |
| SCHEMBL6983686 | 0.86 | CHRM1 (0.32) | SLC6A2SLC6A4 | |
| SCHEMBL6980124 | 0.86 | CHRM1 (0.32) | SLC6A2SLC6A4 | |
| SCHEMBL6976347 | 0.86 | CHRM1 (0.32) | SLC6A2SLC6A4 | |
| SCHEMBL6985201 | 0.85 | EPHX2 (0.45) | MEN1KMT2ATPSAB1 | |
| Hydrochloric Acid SCHEMBL6980788 | 0.85 | CHRM1 (0.31) | SLC6A2SLC6A4 | |
| Hydrochloric Acid SCHEMBL6978492 | 0.85 | EPHX2 (0.45) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0923575-B1 | CYCLIC ETHER COMPOUNDS AS SODIUM CHANNEL MODULATORS | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-03-12 | — | — | EP | disclosed |
| US-6172085-B1 | CENTRAL NERVOUS SYSTEM AND PSYCHOLOGICAL DISORDERS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-01-09 | — | — | US | disclosed |