Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 1/20 | 0.52 |
| ▸ | USP1 | O94782 | 2/20 | 0.43 |
| ▸ | WDR48 | Q8TAF3 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.39 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6987909 | 0.99 | NPY5R (0.51) | NPY5RUSP1WDR48L3MBTL1CYP11B1 | |
| SCHEMBL12692422 | 0.77 | NPY5R (0.64) | NPY5RUSP1WDR48CYP11B1CYP11B2 | |
| SCHEMBL29295367 | 0.73 | USP1 (0.49) | NPY5RUSP1WDR48CYP11B1CYP11B2 | |
| SCHEMBL29293345 | 0.72 | NPY5R (0.46) | NPY5RUSP1WDR48CYP11B1CYP11B2 | |
| SCHEMBL13057724 | 0.69 | NPY5R (0.49) | NPY5RUSP1WDR48CYP11B1CYP11B2 | |
| SCHEMBL6983163 | 0.69 | NPY5R (0.46) | NPY5RUSP1WDR48CYP11B1CYP11B2 | |
| SCHEMBL5793081 | 0.69 | CYP11B2 (0.44) | CYP11B1CYP11B2CYP1A2CYP3A4NPC1 | |
| SCHEMBL13057058 | 0.69 | NPY5R (0.54) | NPY5RUSP1WDR48CYP11B1CYP11B2 | |
| Hydrochloric Acid SCHEMBL6987907 | 0.68 | NPY5R (0.46) | NPY5RUSP1WDR48CYP11B1CYP11B2 | |
| SCHEMBL13056285 | 0.68 | NPY5R (0.48) | NPY5RUSP1WDR48CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030130340-A1 | Novel benzothiophene derivatives | DAIICHI PHARMACEUTICAL CO. LTD. | 2003-07-10 | — | — | US | disclosed |
| EP-1283209-A1 | NOVEL BENZOTHIOPHENE DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2003-02-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030130340-A1 | Novel benzothiophene derivatives | CYP17A1, CYP21A2, HSD17B1 | NPY5R 1329/4885USP1 1613/4885WDR48 2986/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.