⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11254676 | 0.82 | TSHR (0.47) | — | |
| SCHEMBL11722823 | 0.79 | — | — | |
| SCHEMBL483277 | 0.78 | — | — | |
| SCHEMBL18549310 | 0.78 | — | — | |
| SCHEMBL11244890 | 0.76 | FAAH (0.48) | — | |
| SCHEMBL97743 | 0.76 | — | — | |
| SCHEMBL4202343 | 0.74 | ACE (0.38) | — | |
| SCHEMBL30570 | 0.73 | — | — | |
| SCHEMBL6261613 | 0.73 | FAAH (0.58) | — | |
| SCHEMBL353991 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101704796-A | Preparation method of 3-morpholone | SINOCHEM NINGBO GROUP CO LTD | 2010-05-12 | — | — | CN | claimed |
| US-20180201620-A1 | Selective Modulators of the Activity of the GPR55 Receptor: Chromenopyrazole Derivatives | CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (CSIC) (ES) | 2018-07-19 | — | — | US | disclosed |
| US-9724417-B2 | Nanocarriers with multi-photon response elements | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-08-08 | — | — | US | disclosed |
| US-8828383-B2 | Nanocarriers with multi-photon response elements | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2014-09-09 | — | — | US | disclosed |
| US-8759537-B2 | 3H-imidazo [4, 5-C] pyridine-6-carboxamides as anti-inflammatory agents | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-06-24 | — | — | US | disclosed |
| US-8586604-B2 | Inhibitors of the microsomal prostaglandin E2 synthase-1 | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-11-19 | — | — | US | disclosed |
| US-20120259267-A1 | Chemically Amplified Response Strategies for Medical Sciences | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-10-11 | — | — | US | disclosed |
| US-20120214786-A1 | NEW COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-08-23 | — | — | US | disclosed |
| US-20120208839-A1 | NEW COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-08-16 | — | — | US | disclosed |
| CN-101704796-B | Preparation method of 3-morpholone | SINOCHEM NINGBO (GROUP) CO., LTD. (CN) | 2011-12-21 | — | — | CN | disclosed |
| CN-101704796-A | Preparation method of 3-morpholone | SINOCHEM NINGBO GROUP CO LTD | 2010-05-12 | — | — | CN | disclosed |
| EP-0985671-B1 | PYRIDOCARBAZOLE DERIVATIVES HAVING cGMP-PDE INHIBITORY EFFECT | MOCHIDA PHARM CO LTD (JP) | 2003-04-02 | — | — | EP | disclosed |
| US-6197768-B1 | THERAPY, PREVENTION ISCHEMIC HEART DISEASE | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2001-03-06 | — | — | US | disclosed |
| EP-0985671-A1 | PYRIDOCARBAZOLE DERIVATIVES HAVING cGMP-PDE INHIBITORY EFFECT | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2000-03-15 | — | — | EP | disclosed |
| US-6018046-A | SELECTIVE ACTION IN INHIBITING CYCLIC GMP-PHOSPHODIESTERASE (CGMP-PDE); PHARMACEUTICALS FOR TREATING DISEASES AGAINST WHICH THE INHIBITORY ACTION IS EFFECTIVE, SUCH AS PULMONARY HYPERTENSION | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2000-01-25 | — | — | US | disclosed |