⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1685816 | 0.85 | — | — | |
| SCHEMBL11254676 | 0.85 | TSHR (0.47) | — | |
| SCHEMBL4850918 | 0.81 | ACE (0.36) | — | |
| SCHEMBL4850927 | 0.81 | ACE (0.36) | — | |
| SCHEMBL2418248 | 0.80 | — | — | |
| SCHEMBL11244890 | 0.79 | FAAH (0.48) | — | |
| SCHEMBL1304773 | 0.78 | — | — | |
| SCHEMBL30570 | 0.76 | — | — | |
| SCHEMBL6983241 | 0.76 | — | — | |
| SCHEMBL6261613 | 0.76 | FAAH (0.58) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 101 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112521350-B | Synthetic method of 3-methylamino tetrahydrofuran | 江苏广域化学有限公司 | 2023-01-03 | — | — | CN | claimed |
| CN-112521350-A | Synthetic method of 3-methylamino tetrahydrofuran | 江苏广域化学有限公司 | 2021-03-19 | — | — | CN | claimed |
| CN-106941176-B | A kind of SnO as negative electrode of lithium ion battery2/ C nano medicine ball and preparation method thereof | 广东工业大学 | 2019-09-27 | — | — | CN | claimed |
| CN-106941176-A | A kind of SnO as lithium ion battery negative2/ C nano medicine ball and preparation method thereof | 广东工业大学 | 2017-07-11 | — | — | CN | claimed |
| US-8158406-B2 | reduction of keto compounds, in particular of 4-halo-3-oxobutyric acid esters, to the corresponding R-alcohols or S-4-halo-3-hydroxybutyric acid esters, respectively, using an R-specific oxidoreductase in the presence of a cofactor such as NAD(P)H | IEP GMBH (DE) | 2012-04-17 | — | — | US | claimed |
| EP-1926821-B1 | Method of enantioselective enzymatic reduction of keto compounds | IEP GMBH (DE) | 2011-04-20 | — | — | EP | claimed |
| CN-101575329-B | Preparation method of tetrahydrothiophene-3-ketone and intermediate | CHONGQING FUAN PHARMACEUTICAL CO LTD | 2011-01-26 | — | — | CN | claimed |
| CN-101575329-A | Preparation method of tetrahydrothiophene-3-ketone and intermediate | CHONGQING FUAN PHARMACEUTICAL (CN) | 2009-11-11 | — | — | CN | claimed |
| EP-1851322-B1 | METHOD FOR THE ENANTIOSELECTIVE ENZYMATIC REDUCTION OF KETO COMPOUNDS | IEP GMBH (DE) | 2009-10-21 | — | — | EP | claimed |
| US-20080233619-A1 | Process For the Enantioselective Enzymatic Reduction of Keto Compounds | IEP GMBH (DE) | 2008-09-25 | — | — | US | claimed |
| US-20080153140-A1 | Method for the Enantioselective Enzymatic Reduction of Keto Compounds | IEP GMBH (DE) | 2008-06-26 | — | — | US | claimed |
| EP-1926821-A1 | METHOD OF ENANTIOSELECTIVE ENZYMATIC REDUCTION OF KETO COMPOUNDS | IEP GmbH (DE) | 2008-06-04 | — | — | EP | claimed |
| EP-1851322-A1 | METHOD FOR THE ENANTIOSELECTIVE ENZYMATIC REDUCTION OF KETO COMPOUNDS | IEP GmbH (DE) | 2007-11-07 | — | — | EP | claimed |
| WO-2007036257-A1 | METHOD OF ENANTIOSELECTIVE ENZYMATIC REDUCTION OF KETO COMPOUNDS | IEP GMBH (DE) | 2007-04-05 | — | — | WO | claimed |
| WO-2006087235-A1 | METHOD FOR THE ENANTIOSELECTIVE ENZYMATIC REDUCTION OF KETO COMPOUNDS | IEP GMBH (DE) | 2006-08-24 | — | — | WO | claimed |
| WO-2025137516-A1 | FLUORINATED MONOMERS, ANION EXCHANGE POLYMERS AND METHODS OF MAKING THE SAME | THE CHEMOURS COMPANY FC, LLC (US) | 2025-06-26 | — | — | WO | disclosed |
| CN-116284020-B | Preparation method of pranoprofen | 济宁学院 | 2024-06-18 | — | — | CN | disclosed |
| US-4044054-A | 2-Oxo-3-alkenyl dimethylamine | CALGON CORPORATION (US) | 1977-08-23 | — | — | US | disclosed |
| US-4028356-A | Triazinobenzodiazepines | THE UPJOHN COMPANY (US) | 1977-06-07 | — | — | US | disclosed |
| US-3959367-A | Oxidation of halo-olefins | THE DOW CHEMICAL COMPANY (US) | 1976-05-25 | — | — | US | disclosed |