Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 10/20 | 0.46 |
| ▸ | DRD3 | P35462 | 10/20 | 0.46 |
| ▸ | LSS | P48449 | 1/20 | 0.43 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6984706 | 0.90 | ALDH1A1 (0.40) | KCNA5HPGDPOLBALDH1A1 | |
| SCHEMBL6978721 | 0.89 | MEN1 (0.48) | DRD2DRD3HPGDCA12CA1 | |
| SCHEMBL6984892 | 0.89 | KDM4E (0.45) | DRD2DRD3LSSKCNA5CA12 | |
| SCHEMBL6982088 | 0.88 | ALDH1A1 (0.48) | POLBALDH1A1TSHR | |
| SCHEMBL8579639 | 0.88 | DRD3 (0.40) | DRD2DRD3HPGDALDH1A1 | |
| SCHEMBL6976776 | 0.86 | CA12 (0.44) | HPGDCA12CA1CA2CA7 | |
| SCHEMBL6981795 | 0.83 | POLB (0.47) | DRD3CA12CA1CA2CA7 | |
| SCHEMBL6983252 | 0.75 | CACNA1B (0.36) | DRD3 | |
| SCHEMBL6974103 | 0.74 | NPC1 (0.48) | DRD3POLBALDH1A1TSHR | |
| SCHEMBL6983343 | 0.70 | DRD2 (0.46) | DRD2DRD3LSSKCNA5HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0923575-B1 | CYCLIC ETHER COMPOUNDS AS SODIUM CHANNEL MODULATORS | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-03-12 | — | — | EP | disclosed |
| US-6172085-B1 | CENTRAL NERVOUS SYSTEM AND PSYCHOLOGICAL DISORDERS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-01-09 | — | — | US | disclosed |