Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.53 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.53 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.53 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.53 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.53 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6983379 | 0.81 | ITGB3 (0.69) | KMT2ATDP1 | |
| SCHEMBL6978278 | 0.81 | KMT2A (0.47) | KMT2ATDP1POLBMAPTHPGD | |
| SCHEMBL6980785 | 0.79 | CA12 (0.59) | KMT2ASMN1; SMN2POLBMAPTHPGD | |
| Hydrochloric Acid SCHEMBL6983894 | 0.78 | CA12 (0.57) | KMT2ASMN1; SMN2POLBMAPTHPGD | |
| SCHEMBL8072019 | 0.78 | ITGB3 (0.47) | KMT2ASMN1; SMN2TDP1POLBMAPT | |
| SCHEMBL3093136 | 0.78 | KMT2A (0.55) | KMT2AHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL28030360 | 0.78 | SMN1; SMN2 (0.67) | KMT2ASMN1; SMN2HDAC3HDAC4HDAC1 | |
| SCHEMBL3081465 | 0.78 | KMT2A (0.55) | KMT2AHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL3913781 | 0.77 | HDAC3 (0.68) | SMN1; SMN2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL5356584 | 0.76 | SMN1; SMN2 (0.73) | SMN1; SMN2HDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0539343-B1 | Substituted heterocyclic derivatives useful as platelet aggregation inhibitors | MONSANTO CO (US) | 2000-07-26 | — | — | EP | claimed |