Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.32 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.32 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6972794 | 0.72 | KDM4E (0.36) | CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL6980313 | 0.70 | CYP2A6 (0.43) | CYP2A6PTGS1 | |
| SCHEMBL9529453 | 0.70 | TUBB4A (0.45) | CYP2A6CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL4444860 | 0.68 | CYP2A6 (0.44) | CYP2A6PTGS1 | |
| SCHEMBL6976417 | 0.68 | — | — | |
| SCHEMBL6981917 | 0.68 | CSNK2A2 (0.33) | CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL30856387 | 0.68 | CYP2A6 (0.41) | CYP2A6 | |
| SCHEMBL7067833 | 0.67 | ERN1 (0.47) | CYP2A6 | |
| SCHEMBL3770652 | 0.67 | ERN1 (0.43) | CYP2A6 | |
| SCHEMBL9779028 | 0.66 | ERN1 (0.42) | CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1020427-B1 | Agent for potentiating nerve growth factor activity containing 1,2-ethanediol derivative or salt thereof | TOYAMA CHEMICAL CO LTD (JP) | 2003-10-01 | — | — | EP | disclosed |
| EP-1223169-A1 | Agent for potentiating nerve growth factor activity containg 1,2-ethanediol derivate or salt thereof | TOYAMA CHEMICAL CO., LTD. (JP) | 2002-07-17 | — | — | EP | disclosed |
| EP-0790246-B1 | POTENTIATOR FOR NERVE GROWTH FACTOR ACTIVITY CONTAINING 1,2-ETHANEDIOL DERIVATIVE OR SALT THEREOF | TOYAMA CHEMICAL CO LTD (JP) | 2002-01-16 | — | — | EP | disclosed |
| US-6103754-A | Agent for potentiating nerve growth factor activity containing 1,2-ethanediol derivative or salt thereof | TOYAMA CHEMICAL CO., LTD. (JP) | 2000-08-15 | — | — | US | disclosed |
| EP-1020427-A1 | Agent for potentiating nerve growth factor activity containing 1,2-ethanediol derivative or salt thereof | TOYAMA CHEMICAL CO., LTD. (JP) | 2000-07-19 | — | — | EP | disclosed |
| US-6034119-A | Agent for potentiating nerve growth factor activity containing 1,2-ethanediol derivative or salt thereof | TOYAMA CHEMICAL CO., LTD. (JP) | 2000-03-07 | — | — | US | disclosed |
| US-5968935-A | ADMINISTERING TO TREAT NERVOUS SYSTEM DISORDERS | TOYAMA CHEMICAL CO.., LTD. (JP) | 1999-10-19 | — | — | US | disclosed |
| US-5922721-A | USE IN TREATING ALZHEIMER'S DISEASE, HUNTINGTON'S CHOREA, AMYOTROPHIC LATERAL SCLEROSIS AND TRAUAMTIC NERVE INJURIES | TOYAMA CHEMICAL CO., LTD. (JP) | 1999-07-13 | — | — | US | disclosed |
| US-5807887-A | COGNITION ACTIVATOR; ALZHEIMER*S, HUNTINGTON DISEASE | TOYAMA CHEMICAL CO., LTD. (JP) | 1998-09-15 | — | — | US | disclosed |
| EP-0790246-A1 | POTENTIATOR FOR NERVE GROWTH FACTOR ACTIVITY CONTAINING 1,2-ETHANEDIOL DERIVATIVE OR SALT THEREOF | TOYAMA CHEMICAL CO., LTD. (JP) | 1997-08-20 | — | — | EP | disclosed |