Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | VKORC1 | Q9BQB6 | 2/20 | 0.38 |
| ▸ | PPOX | P50336 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8140543 | 0.95 | KDM4E (0.43) | TSHRKDM4EMAPTHTTLMNA | |
| SCHEMBL8143426 | 0.86 | HTT (0.40) | TSHRKDM4EMAPTHTTLMNA | |
| SCHEMBL3843668 | 0.86 | HTT (0.40) | TSHRKDM4EMAPTHTTLMNA | |
| SCHEMBL3843016 | 0.84 | HTT (0.39) | TSHRKDM4EMAPTHTTLMNA | |
| SCHEMBL3849979 | 0.82 | TSHR (0.48) | TSHRKDM4EMAPTHTTLMNA | |
| SCHEMBL6985171 | 0.74 | TSHR (0.46) | TSHRKDM4EMAPTHTTLMNA | |
| SCHEMBL8124540 | 0.72 | TSHR (0.43) | TSHRKDM4EMAPTHTTLMNA | |
| SCHEMBL23216550 | 0.68 | QDPR (0.41) | TSHRKDM4EMAPTSLC6A3TP53 | |
| SCHEMBL29745351 | 0.68 | QDPR (0.41) | TSHRKDM4EMAPTSLC6A3TP53 | |
| SCHEMBL6989202 | 0.68 | TSHR (0.39) | TSHRKDM4EMAPTHTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1345897-A1 | CHEMICAL PROCESS AND NEW INTERMEDIATES | SANOFI-SYNTHELABO (FR) | 2003-09-24 | — | — | EP | disclosed |
| WO-2002044150-A1 | CHEMICAL PROCESS AND NEW INTERMEDIATES | SANOFI-SYNTHELABO (FR) | 2002-06-06 | — | — | WO | disclosed |