Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | PPOX | P50336 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | STAT3 | P40763 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6983688 | 0.74 | TSHR (0.46) | TSHRLMNAMAPTKDM4EHTT | |
| SCHEMBL1565128 | 0.73 | TAS1R3 (0.43) | TSHRLMNAMAPTKMT2ASMN1; SMN2 | |
| SCHEMBL8140543 | 0.69 | KDM4E (0.43) | TSHRLMNAMAPTKDM4EHTT | |
| SCHEMBL6703970 | 0.68 | ACHE (0.43) | TSHRLMNAMAPTKDM4EHTT | |
| SCHEMBL6702783 | 0.68 | HTR4 (0.47) | TSHRLMNAKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL6985165 | 0.68 | TSHR (0.44) | TSHRLMNAMAPTKDM4EHTT | |
| SCHEMBL6985850 | 0.67 | TSHR (0.38) | TSHRLMNAMAPTKDM4EHTT | |
| SCHEMBL2651665 | 0.65 | SLC6A3 (0.62) | LMNA | |
| SCHEMBL6699852 | 0.62 | ACHE (0.47) | TSHRLMNAMAPTKDM4EALDH1A1 | |
| SCHEMBL2481341 | 0.62 | HTR4 (0.66) | TSHRKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1345897-A1 | CHEMICAL PROCESS AND NEW INTERMEDIATES | SANOFI-SYNTHELABO (FR) | 2003-09-24 | — | — | EP | disclosed |
| WO-2002044150-A1 | CHEMICAL PROCESS AND NEW INTERMEDIATES | SANOFI-SYNTHELABO (FR) | 2002-06-06 | — | — | WO | disclosed |