Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | PPOX | P50336 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6985171 | 0.75 | TSHR (0.46) | TSHRPPOXLMNATP53PKM | |
| SCHEMBL6985850 | 0.72 | TSHR (0.38) | TSHRPPOXLMNATP53PKM | |
| SCHEMBL6983688 | 0.68 | TSHR (0.46) | TSHRPPOXLMNATP53PKM | |
| SCHEMBL6703970 | 0.64 | ACHE (0.43) | TSHRPPOXLMNAKDM4EMAPT | |
| SCHEMBL6702783 | 0.63 | HTR4 (0.47) | TSHRLMNAKDM4EACHESMN1; SMN2 | |
| SCHEMBL8140543 | 0.62 | KDM4E (0.43) | TSHRLMNATP53PKMALOX15 | |
| SCHEMBL6987350 | 0.62 | MEN1 (0.45) | TSHRHTTALDH1A1MEN1KMT2A | |
| SCHEMBL1565128 | 0.62 | TAS1R3 (0.43) | TSHRLMNAMAPTSMN1; SMN2MAPK1 | |
| SCHEMBL8146658 | 0.61 | TSHR (0.44) | TSHRHTR2AKDM4EALDH1A1 | |
| Chloroneb SCHEMBL22739 | 0.60 | GAA (0.64) | TSHRPKMHTR2AHTR2CKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1345897-A1 | CHEMICAL PROCESS AND NEW INTERMEDIATES | SANOFI-SYNTHELABO (FR) | 2003-09-24 | — | — | EP | disclosed |
| WO-2002044150-A1 | CHEMICAL PROCESS AND NEW INTERMEDIATES | SANOFI-SYNTHELABO (FR) | 2002-06-06 | — | — | WO | disclosed |