Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | STAT3 | P40763 | 1/20 | 0.34 |
| ▸ | CUL4A | Q13619 | 1/20 | 0.34 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.34 |
| ▸ | CTSA | P10619 | 6/20 | 0.34 |
| ▸ | PPOX | P50336 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6741291 | 0.81 | MAPT (0.37) | MAPTNPC1RAB9APOLBNPSR1 | |
| SCHEMBL6738558 | 0.80 | STING1 (0.37) | MAPTNPC1RAB9APOLBNPSR1 | |
| SCHEMBL7089379 | 0.78 | NPC1 (0.36) | MAPTNPC1RAB9APOLBNPSR1 | |
| SCHEMBL6987268 | 0.76 | ALPL (0.41) | MAPTKDM4EKMT2AMEN1CTSA | |
| SCHEMBL6742589 | 0.74 | KDM4E (0.40) | MAPTNPC1RAB9APOLBNPSR1 | |
| SCHEMBL6740540 | 0.74 | HSP90AA1 (0.36) | MAPTNPC1ALDH1A1KDM4EKMT2A | |
| SCHEMBL2467701 | 0.74 | LMNA (0.36) | MAPTNPC1RAB9APOLBNPSR1 | |
| SCHEMBL2467937 | 0.70 | HSP90AA1 (0.40) | MAPTNPC1RAB9APOLBNPSR1 | |
| SCHEMBL6741788 | 0.70 | ALPL (0.38) | MAPTNPC1RAB9APOLBNPSR1 | |
| SCHEMBL6742932 | 0.70 | FFAR4 (0.36) | MAPTNPSR1SMN1; SMN2ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1289970-A1 | 3-ARYLISOTHIAZOLES AND THEIR USE AS HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 2003-03-12 | — | — | EP | disclosed |
| WO-2001087863-A1 | 3-ARYLISOTHIAZOLES AND THEIR USE AS HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 2001-11-22 | — | — | WO | disclosed |