Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6984258 | 0.82 | — | — | |
| SCHEMBL6979535 | 0.75 | TRPV3 (0.39) | L3MBTL1ALDH1A1GAATSHRMAPT | |
| SCHEMBL6981819 | 0.72 | PDE4A (0.35) | — | |
| SCHEMBL10954259 | 0.66 | NFE2L2 (0.43) | L3MBTL1ALDH1A1GAASMN1; SMN2MAPT | |
| SCHEMBL10953962 | 0.64 | GRM5 (0.43) | L3MBTL1SLC6A3 | |
| SCHEMBL12483137 | 0.64 | DRD4 (0.35) | L3MBTL1CYP3A4TSHR | |
| SCHEMBL30436204 | 0.64 | DRD4 (0.35) | L3MBTL1CYP3A4TSHR | |
| SCHEMBL31616873 | 0.64 | L3MBTL1 (0.46) | L3MBTL1ALDH1A1GAASMN1; SMN2CYP3A4 | |
| SCHEMBL17667865 | 0.64 | L3MBTL1 (0.46) | L3MBTL1ALDH1A1GAASMN1; SMN2CYP3A4 | |
| SCHEMBL179546 | 0.64 | L3MBTL1 (0.46) | L3MBTL1ALDH1A1GAASMN1; SMN2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0946546-B1 | PYRIDIN-2-YL-METHYLAMINE DERIVATIVES, METHOD OF PREPARING AND APPLICATION AS MEDICINE | PF MEDICAMENT (FR) | 2003-06-25 | — | — | EP | disclosed |
| US-6020345-A | Pyridin-2-yl-methylamine derivatives, method of preparing and application as medicine | PIERRE FABRE MEDICAMENT (FR) | 2000-02-01 | — | — | US | disclosed |
| EP-0946546-A1 | PYRIDIN-2-YL-METHYLAMINE DERIVATIVES, METHOD OF PREPARING AND APPLICATION AS MEDICINE | PIERRE FABRE MEDICAMENT (FR) | 1999-10-06 | — | — | EP | disclosed |
| WO-1998022459-A1 | PYRIDIN-2-YL-METHYLAMINE DERIVATIVES, METHOD OF PREPARING AND APPLICATION AS MEDICINE | PIERRE FABRE MEDICAMENT (FR) | 1998-05-28 | — | — | WO | disclosed |