Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.48 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22234262 | 0.81 | KEAP1 (0.51) | HTTNPSR1LMNAPOLBKEAP1 | |
| SCHEMBL6983882 | 0.80 | ALDH1A1 (0.48) | HTTLMNAKEAP1NFE2L2ALDH1A1 | |
| SCHEMBL11471689 | 0.76 | TSHR (0.50) | HTTNPSR1MEN1KMT2ALMNA | |
| SCHEMBL11468790 | 0.76 | TSHR (0.50) | HTTNPSR1MEN1KMT2ALMNA | |
| SCHEMBL11472070 | 0.76 | TSHR (0.50) | HTTNPSR1MEN1KMT2ALMNA | |
| SCHEMBL11467633 | 0.76 | TSHR (0.50) | HTTNPSR1MEN1KMT2ALMNA | |
| SCHEMBL11472114 | 0.76 | TSHR (0.50) | HTTNPSR1MEN1KMT2ALMNA | |
| SCHEMBL11478307 | 0.76 | TSHR (0.50) | HTTNPSR1MEN1KMT2ALMNA | |
| SCHEMBL11473168 | 0.76 | TSHR (0.50) | HTTNPSR1MEN1KMT2ALMNA | |
| SCHEMBL6984896 | 0.74 | ABCB1 (0.59) | HTTMEN1KMT2ALMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991624-B1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA (DE) | 2003-11-19 | — | — | EP | disclosed |