Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 16/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 9/20 | 0.53 |
| ▸ | OPRM1 | P35372 | 9/20 | 0.53 |
| ▸ | OPRD1 | P41143 | 9/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6983993 | 1.00 | OPRK1 (0.53) | OPRK1CYP2D6OPRM1OPRD1 | |
| SCHEMBL9450063 | 0.89 | OPRK1 (0.65) | OPRK1CYP2D6OPRM1OPRD1 | |
| SCHEMBL28743229 | 0.89 | OPRK1 (0.58) | OPRK1CYP2D6OPRM1OPRD1 | |
| SCHEMBL6977759 | 0.89 | OPRK1 (0.58) | OPRK1CYP2D6OPRM1OPRD1 | |
| SCHEMBL6977756 | 0.89 | OPRK1 (0.58) | OPRK1CYP2D6OPRM1OPRD1 | |
| SCHEMBL6982844 | 0.88 | CCR5 (0.58) | OPRK1CYP2D6OPRM1OPRD1 | |
| SCHEMBL6982841 | 0.88 | CCR5 (0.58) | OPRK1CYP2D6OPRM1OPRD1 | |
| SCHEMBL6974429 | 0.86 | OPRK1 (0.54) | OPRK1CYP2D6OPRM1OPRD1 | |
| SCHEMBL6974434 | 0.86 | OPRK1 (0.54) | OPRK1CYP2D6OPRM1OPRD1 | |
| SCHEMBL6983806 | 0.86 | OPRK1 (0.61) | OPRK1CYP2D6OPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0817772-B1 | PYRROLIDINYL HYDROXAMIC ACID COMPOUNDS AND THEIR PRODUCTION PROCESS | PFIZER (US) | 2003-01-29 | — | — | EP | disclosed |