Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.72 |
| ▸ | NPC1 | O15118 | 7/20 | 0.72 |
| ▸ | MAPT | P10636 | 1/20 | 0.72 |
| ▸ | PKM | P14618 | 1/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.67 |
| ▸ | MEN1 | O00255 | 4/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.53 |
| ▸ | CASP3 | P42574 | 1/20 | 0.53 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.53 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.53 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | FLT3 | P36888 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6983615 | 0.84 | PPARA (0.60) | RAB9ANPC1MAPTKMT2AMEN1 | |
| SCHEMBL30051982 | 0.78 | MEN1 (0.77) | RAB9ANPC1MAPTPKMKMT2A | |
| SCHEMBL9637653 | 0.78 | MEN1 (0.77) | RAB9ANPC1MAPTPKMKMT2A | |
| SCHEMBL10665495 | 0.76 | RAB9A (0.79) | RAB9ANPC1MAPTPKMKMT2A | |
| Bromide SCHEMBL29417998 | 0.76 | MEN1 (0.74) | RAB9ANPC1MAPTPKMKMT2A | |
| Hydrochloric Acid SCHEMBL29388210 | 0.76 | MEN1 (0.74) | RAB9ANPC1MAPTPKMKMT2A | |
| SCHEMBL1514407 | 0.76 | RAB9A (0.70) | RAB9ANPC1MAPTPKMKMT2A | |
| SCHEMBL22926425 | 0.76 | RAB9A (1.00) | RAB9ANPC1MAPTPKMKMT2A | |
| SCHEMBL9190814 | 0.74 | KMT2A (1.00) | RAB9ANPC1MAPTPKMKMT2A | |
| SCHEMBL22926672 | 0.74 | FPR2 (0.74) | RAB9ANPC1MAPTPKMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1030835-B1 | UREA DERIVATIVES AND THEIR USE AS INTEGRIN INHIBITORS | ASTRAZENECA UK LTD (GB) | 2003-01-22 | — | — | EP | disclosed |
| US-6344570-B1 | ANTISTICKING AGENTS FOR CELLS | ASTRAZENECA UK LIMITED (GB) | 2002-02-05 | — | — | US | disclosed |
| EP-1030835-A2 | UREA DERIVATIVES AND THEIR USE AS INTEGRIN INHIBITORS | AstraZeneca UK Limited (GB) | 2000-08-30 | — | — | EP | disclosed |
| WO-1999024398-A2 | UREA DERIVATIVES AND THEIR USE AS INTEGRIN INHIBITORS | ASTRAZENECA UK LIMITED (GB) | 1999-05-20 | — | — | WO | disclosed |