SCHEMBL6984166

SCHEMBL6984166

Cc1c(C(=O)O)ccc2sc(Cl)nc12

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.44
ALDH1A1 P00352 3/20 0.42
TSHR P16473 2/20 0.42
HPGD P15428 1/20 0.42
NPC1 O15118 6/20 0.40
RAB9A P51151 5/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
ATM Q13315 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
MGLL Q99685 1/20 0.38
SMN1; SMN2 Q16637 3/20 0.38
KDM4E B2RXH2 1/20 0.38
POLB P06746 1/20 0.38
GABRP O00591 1/20 0.38
GABRD O14764 1/20 0.38
GABRA1 P14867 1/20 0.38
GABRB1 P18505 1/20 0.38
GABRG2 P18507 1/20 0.38
GABRB3 P28472 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6476488 0.83 MAPT (0.46) MAPTALDH1A1NPC1RAB9AMEN1
SCHEMBL6979290 0.78 MAPT (0.49) MAPTALDH1A1NPC1RAB9AMEN1
SCHEMBL6984168 0.77 ALDH1A1 (0.44) MAPTALDH1A1TSHRHPGDNPC1
SCHEMBL3314508 0.77 ALDH1A1 (0.50) MAPTALDH1A1TSHRHPGDRAB9A
SCHEMBL7836861 0.75 ALDH1A1 (0.47) MAPTALDH1A1HPGDNPC1RAB9A
Hydrochloric Acid SCHEMBL10572818 0.75 ALDH1A1 (0.49) MAPTALDH1A1TSHRHPGDRAB9A
SCHEMBL6983756 0.75 MAPT (0.36) MAPTALDH1A1HPGDNPC1RAB9A
SCHEMBL6184530 0.72 MAPT (0.46) MAPTALDH1A1NPC1RAB9AMEN1
SCHEMBL27795722 0.71 ALDH1A1 (0.44) MAPTALDH1A1TSHRHPGDNPC1
SCHEMBL21642573 0.70 GABRP (0.40) MAPTALDH1A1TSHRHPGDMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1177194-B1 4-(3',4'-HETEROCYCLYL BENZOYL) PYRAZOLES AS HERBICIDAL AGENTS BASF AG (DE) 2003-09-17 EP disclosed
US-6541423-B1 Controlling vegatation BASF AKTIENGESELLSCHAFT (DE) 2003-04-01 US disclosed
EP-1177194-A1 4-(3',4'-HETEROCYCLYL BENZOYL) PYRAZOLES AS HERBICIDAL AGENTS BASF AKTIENGESELLSCHAFT (DE) 2002-02-06 EP disclosed
WO-2000068228-A1 4-(3',4'-HETEROCYCLYL BENZOYL) PYRAZOLES AS HERBICIDAL AGENTS BASF AKTIENGESELLSCHAFT (DE) 2000-11-16 WO disclosed