SCHEMBL6983756

SCHEMBL6983756

Cc1c(C(=O)c2cnn(C)c2O)ccc2sc(Cl)nc12

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 10/20 0.36
ALDH1A1 P00352 5/20 0.35
MGLL Q99685 1/20 0.34
LMNA P02545 4/20 0.34
NPC1 O15118 4/20 0.33
RAB9A P51151 3/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
ATM Q13315 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
TP53 P04637 2/20 0.32
HPGD P15428 3/20 0.32
HTT P42858 3/20 0.32
KDM4E B2RXH2 2/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
PPARG P37231 1/20 0.31
NCOA2 Q15596 1/20 0.31
NCOA1 Q15788 1/20 0.31
NCOA3 Q9Y6Q9 1/20 0.31
SLC2A1 P11166 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6982357 0.88 MGLL (0.37) MAPTALDH1A1MGLLLMNANPC1
SCHEMBL7088309 0.84 MAPT (0.39) MAPTALDH1A1LMNANPC1RAB9A
SCHEMBL7157976 0.81 MAPT (0.32) MAPTALDH1A1LMNANPC1RAB9A
SCHEMBL6979351 0.78
SCHEMBL6979923 0.78 MALT1 (0.33)
SCHEMBL6984166 0.75 MAPT (0.44) MAPTALDH1A1MGLLNPC1RAB9A
SCHEMBL9779245 0.73 GABRP (0.34) MAPTALDH1A1LMNANPC1RAB9A
SCHEMBL10724382 0.73 PKM (0.34) MAPTALDH1A1LMNANPC1RAB9A
SCHEMBL6974905 0.73 MGLL (0.36) MAPTALDH1A1MGLLLMNANPC1
SCHEMBL27941481 0.72 SMN1; SMN2 (0.38) MAPTALDH1A1LMNANPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1177194-B1 4-(3',4'-HETEROCYCLYL BENZOYL) PYRAZOLES AS HERBICIDAL AGENTS BASF AG (DE) 2003-09-17 EP disclosed
US-6541423-B1 Controlling vegatation BASF AKTIENGESELLSCHAFT (DE) 2003-04-01 US disclosed