SCHEMBL6984186

SCHEMBL6984186

CCc1nc2c(C)c(C(=O)c3cnn(C)c3O)ccc2o1

nearest known ligand 0.34

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.34
TAS2R8 Q9NYW2 1/20 0.31
PTGES O14684 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6984929 0.86 GAA (0.33) GAA
SCHEMBL6983756 0.72 MAPT (0.36)
SCHEMBL6982357 0.71 MGLL (0.37) GAA
SCHEMBL27941481 0.71 SMN1; SMN2 (0.38)
SCHEMBL6979351 0.69
SCHEMBL6979923 0.69 MALT1 (0.33)
SCHEMBL7088309 0.68 MAPT (0.39) GAA
SCHEMBL7157976 0.68 MAPT (0.32) GAA
SCHEMBL12724676 0.68 AR (0.34)
SCHEMBL12602531 0.67 SMN1; SMN2 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1177194-B1 4-(3',4'-HETEROCYCLYL BENZOYL) PYRAZOLES AS HERBICIDAL AGENTS BASF AG (DE) 2003-09-17 EP disclosed
US-6541423-B1 Controlling vegatation BASF AKTIENGESELLSCHAFT (DE) 2003-04-01 US disclosed