SCHEMBL6979923

SCHEMBL6979923

Cc1c(C(=O)c2cnn(C)c2O)ccc2scnc12

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MALT1 Q9UDY8 3/20 0.33
EGLN1 Q9GZT9 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7160276 0.84 HSD11B1 (0.33) MALT1EGLN1
SCHEMBL6979990 0.84 MALT1 (0.32) MALT1EGLN1
SCHEMBL6979351 0.80
SCHEMBL6982357 0.80 MGLL (0.37) MALT1
SCHEMBL6983648 0.78 KMT2A (0.34) EGLN1
SCHEMBL6983155 0.78 SMN1; SMN2 (0.35)
SCHEMBL6972533 0.78 POLB (0.30)
SCHEMBL6983756 0.78 MAPT (0.36)
SCHEMBL7088309 0.76 MAPT (0.39)
SCHEMBL27941481 0.74 SMN1; SMN2 (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1177194-B1 4-(3',4'-HETEROCYCLYL BENZOYL) PYRAZOLES AS HERBICIDAL AGENTS BASF AG (DE) 2003-09-17 EP disclosed
US-6541423-B1 Controlling vegatation BASF AKTIENGESELLSCHAFT (DE) 2003-04-01 US disclosed