Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6981932 | 0.82 | MBOAT4 (0.35) | KCNH2 | |
| SCHEMBL19696122 | 0.77 | — | — | |
| SCHEMBL6979538 | 0.75 | TRPV3 (0.46) | KCNH2 | |
| SCHEMBL6981824 | 0.72 | PDE4A (0.31) | — | |
| SCHEMBL17408874 | 0.72 | DGAT1 (0.32) | — | |
| SCHEMBL19696094 | 0.72 | — | — | |
| SCHEMBL22838147 | 0.71 | KCNH2 (0.39) | KCNH2 | |
| SCHEMBL31682301 | 0.70 | S1PR4 (0.32) | — | |
| SCHEMBL15971840 | 0.70 | S1PR4 (0.32) | — | |
| SCHEMBL19696076 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0946546-B1 | PYRIDIN-2-YL-METHYLAMINE DERIVATIVES, METHOD OF PREPARING AND APPLICATION AS MEDICINE | PF MEDICAMENT (FR) | 2003-06-25 | — | — | EP | disclosed |
| US-6020345-A | Pyridin-2-yl-methylamine derivatives, method of preparing and application as medicine | PIERRE FABRE MEDICAMENT (FR) | 2000-02-01 | — | — | US | disclosed |