Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 2/20 | 0.36 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 5/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 5/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 4/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.33 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6981261 | 0.84 | SLC7A5 (0.37) | ARSLC7A5EPHX2ELANEADRA1A | |
| SCHEMBL6723581 | 0.84 | ELANE (0.44) | SLC7A5ELANEADRA1AADRA1BKMT2A | |
| SCHEMBL6984283 | 0.83 | SLC7A5 (0.38) | ARSLC7A5EPHX2ELANEADRA1A | |
| SCHEMBL6582605 | 0.82 | SLC7A5 (0.37) | ARSLC7A5EPHX2ELANEADRA1A | |
| SCHEMBL6985192 | 0.81 | KMT2A (0.42) | SLC7A5KMT2AKDM4EMEN1 | |
| SCHEMBL6988917 | 0.80 | SLC7A5 (0.36) | ARSLC7A5EPHX2ELANEADRA1A | |
| SCHEMBL6984974 | 0.77 | SLC6A3 (0.40) | SLC7A5EPHX2KMT2AKDM4E | |
| SCHEMBL6984002 | 0.76 | SMN1; SMN2 (0.40) | SLC7A5AAK1KMT2AKDM4EMEN1 | |
| SCHEMBL6984597 | 0.76 | KMT2A (0.42) | SLC7A5EPHX2KMT2AKDM4E | |
| SCHEMBL6981189 | 0.74 | SLC7A5 (0.37) | SLC7A5EPHX2AAK1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1289954-A1 | SERINE PROTEASE INHIBITORS | ELI LILLY AND COMPANY (US) | 2003-03-12 | — | — | EP | disclosed |
| WO-2001096303-A1 | SERINE PROTEASE INHIBITORS | ELI LILLY AND COMPANY (US) | 2001-12-20 | — | — | WO | disclosed |