Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.37 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
| ▸ | PRKDC | P78527 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6983312 | 0.95 | HTT (0.37) | ATMALDH1A1HTT | |
| SCHEMBL6987419 | 0.88 | ALDH1A1 (0.43) | ALDH1A1HTT | |
| SCHEMBL6987686 | 0.87 | SIGMAR1 (0.45) | ALDH1A1HTT | |
| SCHEMBL6987971 | 0.86 | HTT (0.38) | ALDH1A1HTT | |
| SCHEMBL6987183 | 0.85 | TSHR (0.45) | ALDH1A1HTT | |
| SCHEMBL6987611 | 0.84 | SIGMAR1 (0.44) | — | |
| SCHEMBL6990721 | 0.82 | SIGMAR1 (0.46) | — | |
| SCHEMBL6986812 | 0.82 | ALDH1A1 (0.40) | ATMALDH1A1HTT | |
| SCHEMBL6986605 | 0.82 | HTT (0.48) | ALDH1A1HTT | |
| SCHEMBL6982995 | 0.82 | HRH3 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1313733-A1 | PYRAZOLOPYRIDINE COMPOUND AND PHARMACEUTICAL USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-05-28 | — | — | EP | disclosed |
| WO-2002018382-A1 | PYRAZOLOPYRIDINE COMPOUND AND PHARMACEUTICAL USE THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-03-07 | — | — | WO | disclosed |